AMC(ATEMs Medicinal Cell)
Cartilage-derived Stem Cells
Advantages and Competitiveness of AMC
Limitations of Adult Stems Cells
Injectable Cartilage Tissue Regeneration Therapeutics
Physical properties Gel type: Can be injected with a syringe
High adhesiveness: Easily integrates to host tissue
Animal Cartilage-derived Acellular extracellular Matrix (CAM) material
Features - Original raw biomaterial derived from pig cartilage
- Proprietary process technology to fabricate the raw material into various forms (powder, membrane, 3-D sponge, injectable gel, etc.) and various properties (porosity, surface modification, degradability, solubility, mechanical strength, blending, etc.)
- Excellent biocompatibility and Controlled degradation rate
- Anti-angiogenic effect
Patents - (Registration No. 10-0816395) Method for preparing a cell-derived extracellular matrix membrane (Awarded the "King Sejong Award")
- (Registration No. 10-1772316) Method for producing extracellular matrix membrane derived from biocompatible porcine cartilage capable of regulating in vivo decomposition rate and physical properties, and composition for preventing adhesion containing extracellular matrix derived from porcine cartilage as active ingredient
Papers Extracellular Matrix (ECM) Multilayer Membrane as a Sustained Releasing Growth Factor Delivery System for rhTGF-β3 in Articular Cartilage Repair. PLoS One. 2016
Preparation of Extracellular Matrix Developed Using Porcine Articular Cartilage and In Vitro Feasibility Study of Porcine Articular Cartilage as an Anti-Adhesive Film. Materials (Basel). 2016
In vivo degradation profile of porcine cartilage-derived extracellular matrix powder scaffolds using a non-invasive fluorescence imaging method. J Biomater Sci Polym Ed. 2016
Injectable extracellular matrix hydrogel developed using porcine articular cartilage. Int J Pharm. 2013
Inhibition of blood vessel formation by a chondrocyte-derived extracellular matrix. Biomaterials. 2014
Cartilage engineering using cell-derived extracellular matrix scaffold in vitro. J Biomed Mater Res A. 2010