TECHNOLOGY
AMC(ATEMs Medicinal Cell)
Cartilage-derived Stem Cells
Advantages and Competitiveness of AMC
VS
Limitations of Adult Stems Cells
A-Paste
Injectable Cartilage Tissue Regeneration Therapeutics
| Appearance |  |
|---|---|
| Composition |  |
| Physical properties |
Gel type: Can be injected with a syringe High adhesiveness: Easily integrates to host tissue |
CAM
Animal Cartilage-derived Acellular extracellular Matrix (CAM) material
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| Features |
- Original raw biomaterial derived from pig cartilage - Proprietary process technology to fabricate the raw material into various forms (powder, membrane, 3-D sponge, injectable gel, etc.) and various properties (porosity, surface modification, degradability, solubility, mechanical strength, blending, etc.) - Excellent biocompatibility and Controlled degradation rate - Anti-angiogenic effect |
| Patents |
- (Registration No. 10-0816395) Method for preparing a cell-derived extracellular matrix membrane (Awarded the "King Sejong Award") - (Registration No. 10-1772316) Method for producing extracellular matrix membrane derived from biocompatible porcine cartilage capable of regulating in vivo decomposition rate and physical properties, and composition for preventing adhesion containing extracellular matrix derived from porcine cartilage as active ingredient |
| Papers |
Extracellular Matrix (ECM) Multilayer Membrane as a Sustained Releasing Growth Factor Delivery System for rhTGF-β3 in Articular Cartilage Repair. PLoS One. 2016 Preparation of Extracellular Matrix Developed Using Porcine Articular Cartilage and In Vitro Feasibility Study of Porcine Articular Cartilage as an Anti-Adhesive Film. Materials (Basel). 2016 In vivo degradation profile of porcine cartilage-derived extracellular matrix powder scaffolds using a non-invasive fluorescence imaging method. J Biomater Sci Polym Ed. 2016 Injectable extracellular matrix hydrogel developed using porcine articular cartilage. Int J Pharm. 2013 Inhibition of blood vessel formation by a chondrocyte-derived extracellular matrix. Biomaterials. 2014 Cartilage engineering using cell-derived extracellular matrix scaffold in vitro. J Biomed Mater Res A. 2010 |